Northeastern University
Northeastern University

Institute for Chemical Imaging of Living Systems
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Welcome

Welcome to Northeastern University FBS Portal. This site is designed to automate the use of our Core Facilities and to provide the best possible customer service.

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Our Core Facilities

To learn more about a particular facility or to request access, please click on a facility name below.

Northeastern University

  • Barnett Proteomics Mass Spectrometry Facility
  • Boston Electron Microscopy Core
  • COE Shared Lab Equipment
  • Institute for Chemical Imaging of Living Systems
  • KNMRC
  • Nuclear Magnetic Resonance

Main Contact Info

Guoxin Rong

805 Columbus Ave, ISEC 080
Boston, MA 02115


cils-core@northeastern.edu

(617) 373-4565

Remittance Contact Info

Guoxin Rong

360 Huntington Ave
Guoxin Rong - ISEC 129
Boston, MA 02115


cils-core@northeastern.edu

(617) 373-4565


This facility has not published any Products. Please check back.

The following Products and Services are available within our facility:

Biophysical Core

NanoTemper Monolith NT.Automated

NanoTemper Monolith NT.Automated

  • Fast measurement: Kd in about 10 min
  • Low sample volume
  • Wide Kd range from nM to mM range
  • Immobilization free, in-solution measurements
  • Measurements in complex mixtures

Bio-rad ChemiDoc MP Gel Imager

Bio-rad ChemiDoc MP Gel Imager

  • Located in MU 220D
  • Biology Department Facility; $50/quarter/lab
  • Imaging gels and blots
  • UV Tray: EtBr, RGB/far red/NIR fluorescence, SYBR stain
  • White Tray: Coomassie blue, copper, silver, zinc stains
  • Blue Tray: GelGreen, GelStar, Fluorescein

Flow Core

Beckman Coulter CytoFLEX S

Beckman Coulter CytoFLEX S

  • 4 laser lines (405, 488, 561, 638).
  • 13 color detection
  • Can load tube or various well plates for analysis
  • Violet side scatter for small particle detection
  • Able to interface experiment design into SRT

Beckman Coulter CytoFLEX SRT

Beckman Coulter CytoFLEX SRT

  • 4 laser lines (405, 488, 561, 638).
  • 15 color detection
  • 100nm nozzle
  • Sort into 1-4 tubes, slides, or into various well plates
  • Mixed Mode sorting
  • Violet side scatter for small particle detection

Microscopy Core

ZEISS LSM 800

ZEISS LSM 800

  • Laser line: 405, 488, 561, 640 nm
  • Objective: 5x, 10x, 20x, 40x, 63x
  • Fixed cell/tissue imaging,
  • Image Tiling

ZEISS LSM 880

ZEISS LSM 880

  • Laser line:  405, 458, 488, 514, 561, 594, 640 nm
  • Objective: 10×, 20×, 40×, 40×, 63×
  • Cage incubator, CO2/O2 control,
  • Superresolution (Airyscan)
  • Spectral Unmixing

ZEISS LSM 880 NLO

ZEISS LSM 880 NLO

  • Laser line: 405, 458, 488, 514, 561, 594, 640 nm
  • NIR Laser: tunable line (680-1300 nm); fixed line -1045 nm
  • Objective: 10×, 20×, 20×, 40×, 20×-CLARITY
  • Multi-photon imaging
  • Superresolution (Airyscan)
  • Spectral Unmixing

ZEISS LSM 900/BRUKER NANOWIZARD 4XP

ZEISS LSM 900/BRUKER NANOWIZARD 4XP

  • AFM:
    • DirectOverlay integration with optical microscopy
    • Large scan field of 100 × 100 × 15 µm
    • Atomic lattice resolution
  • Confocal:
    • Laser line: 405, 488, 561, 640 nm
    • Objective: 10×, 20×, 63×
    • Live cell imaging with environmental control 

ZEISS LIGHTSHEET Z1

ZEISS LIGHTSHEET Z1

  • Laser line: 405, 488, 561, 638 nm
  • Objective: 5×, 10×-water, 20×-CLARITY
  • CO2/temperature control,
  • Large scale 3D tissue imaging
  • arivis Vision4D software

Zeiss AXIOZOOM V16

Zeiss AXIOZOOM V16

  • Continuous zoom with high NA
  • Large filed of view
  • Apotome.2 Structured Illumination Module
  • In vivo and model organism Imaging

ZEISS AXIO OBSERVER (DEMO)

ZEISS AXIO OBSERVER (DEMO)

  • Epifluorescence:  DAPI, GFP, DsRed, Cy5
  • Objective:  10x, 20x, 40x, 63x, 100x
  • immunfluorescence labeled tissue or cell culture imaging

Preclinical Imaging Core

BRUKER BIOSPEC 3T MRI

BRUKER BIOSPEC 3T MRI

 

  • Automated animal positioning
  • Multimodal rat/mouse cradle
  • Two body volume coils for rat/mouse
  • SAII 1030 monitoring/gating module
  • Localized MR Spectroscopy
VISUALSONICS ULTRASOUND VEVO F2

VISUALSONICS ULTRASOUND VEVO F2

  • Linear probe: 57-25 MHz For high-resolution mouse cardiovascular, abdominal, reproductive; embryology; tumor imaging (< 14 mm diameter); small rat vascular
  • Linear probe: 29-15 MHz For rat cardiac & abdominal (<400 g); large tumor imaging (<23 mm diameter); all contrast applications
  • Phased probe: 8-4 MHz For large animal cardiology & abdominal

PRECISION XRAD 320

PRECISION XRAD 320

  • Programmable irradiation on cells and animals
  • 320kV, 12.5mA, 4000W
  • 2.5Gy/min at 50cm SSD with beam hardening filter
  • Adjustable collimators and specimen shelf
  • OptiMAX module for 2D X-ray imaging
  • Bioluminescence, fluoroscopy, radioisotopic imaging
  • Real-time specimen viewing

PHOTON ETC IR VIVO

PHOTON ETC IR VIVO

  • Illuminaton: Laser at 670, 760, 808 nm
  • Emission Range: 900-1600 nm
  • Lens: 50mm f/1.4
  • FOV: 5 x 4 to 15.6 x 12.5 cm
  • Heated Stage

Please acknowledge CILS Core in your publication! We suggest the following text in the acknowledgements section of your paper: “We thank the Institute for Chemical Imaging of Living Systems at Northeastern University for consultation and imaging support”

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